Summary
The effect of ionizing radiation on human erythrocyte ghost membranes was studied by following changes in membrane — SH groups and activities of four membrane bound enzymes: Na+K+Mg2+ ATP-ase, Mg2+Ca2+ ATP-ase, Na+K+ ATP-ase, and AChE. Irradiation up to 100 Gy gamma X-rays produced a significant decrease in the activity of ATP-ase and an increase in AChE activity. At higher radiation doses a marked decrease in the activities of all the enzymes was observed. A correlation between radiation-induced perturbations in enzyme activities and changes in membrane — SH groups was found.