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International Journal of Radiation Biology Volume 56, 1989 - Issue 6
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Original Article

Lack of Correlation between Radiosensitivity and Inhibition of DNA Synthesis in Hybrids (A-T × HeLa)

K. Komatsu Radiation Biophysics, Atomic Disease Institute, Nagasaki University School of Medicine, Nagasaki, 852, Japan
,
Y. Okumura Radiological Research Laboratories, College of Physicians & Surgeons of Columbia University, New York, 10032, U.S.A.
,
S. Kodama Radiation Biophysics, Atomic Disease Institute, Nagasaki University School of Medicine, Nagasaki, 852, Japan
,
M. Yoshida Radiological Research Laboratories, College of Physicians & Surgeons of Columbia University, New York, 10032, U.S.A.
&
R.C. Miller Radiation Biophysics, Atomic Disease Institute, Nagasaki University School of Medicine, Nagasaki, 852, Japan
Pages 863-867 | Received 19 Apr 1989, Accepted 19 Jun 1989, Published online: 03 Jul 2009
 
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Summary

Hybrid cells obtained from A-T and D98/AH(HeLa) cells showed normal radiation sensitivity to cell killing, but retained radioresistant DNA synthesis similar to parental A-T cells.

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