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International Journal of Radiation Biology Volume 57, 1990 - Issue 1
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Original Article

In CHEF Electrophoresis a Linear Induction of Dsb Corresponds to a Nonlinear Fraction of Extracted DNA with Dose

D. Blöcher Biomedical Physics Department, King Faisal Specialist Hospital and Research Centre, POB 3354, Riyadh, 11211, Saudi Arabia
Pages 7-12 | Received 12 May 1989, Accepted 14 Aug 1989, Published online: 03 Jul 2009
 
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Summary

A theory for DNA double-strand break (dsb) analysis by pulsed field electro-phoresis is presented, based on the size distribution of DNA fragments, which converts an induction of dsb linear with dose into a nonlinear fraction of extractable DNA, in agreement with experimental observations.

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