Summary
The internal microviscosity of human erythrocytes and porcine lymphocytes was investigated, from the electron-spin resonance spectral characteristics of the nitroxyl spin probe, 4-amino-2,2,6,6-tetramethylpiperidinyloxy. Heat-induced permanent damage to cells was observed as an increase in the intracellular microviscosity of nucleate and enucleate cells. Induction of heat resistance was found for erythrocytes treated with a double heat shock.