Frequencies of X-ray-induced Chromosome Translocations in Human Peripheral Lymphocytes as Detected by in Situ Hybridization Using Chromosome-specific DNA Libraries

Abstract

In situ hybridization with chromosome-specific DNA libraries was used to analyse radiation-induced stable translocations in human peripheral blood lymphocytes. These data were compared with radiation-induced unstable-type aberrations (dicentrics) in the same samples. The results indicate that far more stable aberrations are induced by radiation in comparison to unstable aberrations.