Abstract
The aim of this pilot study was to determine the potential of maintenance with clobazamin patients on methadone who were also benzodiazepine dependent. Five individuals were recruited and four were maintained on clobazam for a minimum of 3 months prior to reduction. Three subjects were abstinent from other benzodiazepines at 3 months. Clobazam was given as a single daily dose and was reported by the clients as less sedating than diazepam. There is potential for clobazam to be used as a maintenance benzodiazepine. [Wickes WA, Darke S, Ross J. Clobazam maintenance among methadone maintenance patients with problematic benzodiazepine use: five case studies. Drug Alcohol Rev 2000;19:401-405]