Cavernous Sinus Involvement by Extramedullary Plasmacytoma of the Sphenoid Sinus

Federico L. Ampil Division of Radiation Oncology, Department of Radiology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA

T. Greg Borski Otolaryngology Head Neck Surgery, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA

Cherie Ann O. Nathan Otolaryngology Head Neck Surgery, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA

Gregory Mulcahy Otolaryngology Head Neck Surgery, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA

Michael Walker Division of Radiation Oncology, Department of Radiology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA

Hong W. Chin Division of Radiation Oncology, Department of Radiology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA

Fred J. Stucker Otolaryngology Head Neck Surgery, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA

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Abstract

A 63-year-old man with cavernous sinus involvement from extramedullary plasmacytoma (EMP) of the sphenoid sinus is described. Transient resolution of retro-orbital headache and continued progression of the locally extensive tumor were noted after chemotherapy was given following a poor response to 5400 cGy of local irradiation. To determine whether adjunctive chemotherapy will improve the outcome of these particular patients, we propose that a randomized trial comparing radiotherapy to chemoradiation be conducted.

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Cavernous Sinus Involvement by Extramedullary Plasmacytoma of the Sphenoid Sinus

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Cavernous Sinus Involvement by Extramedullary Plasmacytoma of the Sphenoid Sinus

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