High Dose Therapy with Autologous Stem Cell Transplantation for Solitary Bone Plasmacytoma Complicated by Local Relapse or Isolated Distant Recurrence

Meletios A. Dimopoulos Department of Clinical Therapeutics, University of Athens, School of Medicine, Athens, Greece

Christos Papadimitriou Department of Clinical Therapeutics, University of Athens, School of Medicine, Athens, Greece

Athanassios Anagnostopoulos Department of Clinical Therapeutics, University of Athens, School of Medicine, Athens, Greece

Dimitrios Mitsibounas Department of Clinical Therapeutics, University of Athens, School of Medicine, Athens, Greece

Jean-Paul Fermand Department of Immuno-Hematology, Hospital Saint-Louis, Paris, France

Abstract

We report three patients with solitary bone plasmacytoma (SBP) who developed either local recurrence within the radiotherapy field or an isolated distal recurrence and who were treated with high dose therapy supported by autologous stem cell transplantation. All patients remain without evidence of disease for 4-10 years after the procedure. High dose therapy may be of value and require further study in patients with SBP who develop local or distant failure.

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High Dose Therapy with Autologous Stem Cell Transplantation for Solitary Bone Plasmacytoma Complicated by Local Relapse or Isolated Distant Recurrence

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High Dose Therapy with Autologous Stem Cell Transplantation for Solitary Bone Plasmacytoma Complicated by Local Relapse or Isolated Distant Recurrence

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