Transcriptome profiling of patient derived xenograft models established from pediatric acute myeloid leukemia patients confirm maintenance of FLT3-ITD mutation

Christina D. DrenbergDivision of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, OH, USA; ;Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA;

Daelynn R. BuelowDivision of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, OH, USA; ;Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA;

Stanley B. PoundsDepartment of Biostatics, St. Jude Children's Research Hospital, Memphis, TN, USA;

Yong-Dong WangDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA;

David FinkelsteinDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA;

Richard J. RahijaAnimal Resource Center, St. Jude Children's Research Hospital, Memphis, TN, USA;

Sheila A. ShurtleffDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA;

Jeffrey E. RubnitzDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA;

Hiroto InabaDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA;

Tanja A. GruberDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA;

Jeffery M. KlcoDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA

Sharyn D. BakerDivision of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, OH, USA; ;Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA; Correspondence[email protected]

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Potential conflict of interest

Disclosure forms provided by the authors are available with the full text of this article at http://dx.doi.org/10.1080/10428194.2016.1187272.

Funding information

This work was supported by the National Cancer Institute of the National Institutes of Health [P30 CA021765], [R01 CA138744], and [F32 CA180513].

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Transcriptome profiling of patient derived xenograft models established from pediatric acute myeloid leukemia patients confirm maintenance of FLT3-ITD mutation

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Transcriptome profiling of patient derived xenograft models established from pediatric acute myeloid leukemia patients confirm maintenance of FLT3-ITD mutation

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