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Letters to the Editor

Sensitive monitoring of acute promyelocytic leukemia by PML-RARA DNA Q-PCR

Ivar O. KommersDepartment of Clinical and Molecular Medicine, Flinders University and Medical Centre, Adelaide, Australia; ;VU University Medical Center, Amsterdam, The Netherlands;

Paul A. BartleyDepartment of Clinical and Molecular Medicine, Flinders University and Medical Centre, Adelaide, Australia;

Bradley BudgenDepartment of Clinical and Molecular Medicine, Flinders University and Medical Centre, Adelaide, Australia;

Sue LathamDepartment of Clinical and Molecular Medicine, Flinders University and Medical Centre, Adelaide, Australia;

Ashanka BeligaswatteDepartment of Clinical and Molecular Medicine, Flinders University and Medical Centre, Adelaide, Australia;

Shane G. SuppleInstitute of Haematology, Royal Prince Alfred Hospital, Sydney, Australia;

Alberto CatalanoInstitute of Haematology, Royal Prince Alfred Hospital, Sydney, Australia;

Harry J. IlandInstitute of Haematology, Royal Prince Alfred Hospital, Sydney, Australia; ;Sydney Medical School, University of Sydney, Sydney, Australia;

Alexander A. MorleyDepartment of Clinical and Molecular Medicine, Flinders University and Medical Centre, Adelaide, Australia;

David M. RossDepartment of Clinical and Molecular Medicine, Flinders University and Medical Centre, Adelaide, Australia; ;School of Medicine, University of Adelaide, Adelaide, AustraliaCorrespondence[email protected]

http://orcid.org/0000-0001-7171-2935

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Acknowledgements

I. K. performed experiments, analyzed data, and wrote the paper. P. B., S. L., and S. S. performed experiments and analyzed data. A. B. provided essential clinical data. A. C. and H. I. analyzed data and wrote the paper. A. M. and D. M. R. designed the research, analyzed data, and wrote the paper.

The authors are grateful to the patients who donated samples to the South Australian Cancer Research Biobank, and to the staff of the Biobank, especially Mrs Carolyn Butcher. A. A. M. holds equity in Monoquant Pty Ltd, which patented the breakpoint detection method used herein.

Potential conflict of interest

Disclosure forms provided by the authors are available with the full text of this article online at http://dx.doi.org/10.1080/10428194.2016.1262033.

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Sensitive monitoring of acute promyelocytic leukemia by PML-RARA DNA Q-PCR

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Sensitive monitoring of acute promyelocytic leukemia by PML-RARA DNA Q-PCR

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