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Leukemia & Lymphoma Volume 59, 2018 - Issue 10
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Letter to the Editor

Genetic markers of stable molecular remission in chronic myeloid leukemia after targeted therapy discontinuation

Svetlana A. SmirnikhinaLaboratory of Mutagenesis, FSBI “Research Centre for Medical Genetics”, Moscow, Russian Federation; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-1558-3048View further author information
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Ekaterina Yu. ChelyshevaScientific and Advisory Department of Chemotherapy of Myeloproliferative disorders, FSFI “National Research Center for Hematology” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation; ORCID Iconhttp://orcid.org/0000-0001-6423-1789View further author information
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Alexander V. LavrovLaboratory of Mutagenesis, FSBI “Research Centre for Medical Genetics”, Moscow, Russian Federation; ;Department of Molecular and Cellular Genetics, The Russian National Research Medical University Named after N.I. Pirogov, Moscow, Russian FederationORCID Iconhttp://orcid.org/0000-0003-4962-6947View further author information
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Konstantin S. Kochergin-NikitskyLaboratory of Mutagenesis, FSBI “Research Centre for Medical Genetics”, Moscow, Russian Federation; ORCID Iconhttp://orcid.org/0000-0002-0096-4542View further author information
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Ivan V. MozgovoyDepartment of Molecular and Cellular Genetics, The Russian National Research Medical University Named after N.I. Pirogov, Moscow, Russian FederationView further author information
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Elmira P. AdilgereevaLaboratory of Mutagenesis, FSBI “Research Centre for Medical Genetics”, Moscow, Russian Federation; ORCID Iconhttp://orcid.org/0000-0002-6440-0500View further author information
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Oleg A. ShukhovScientific and Advisory Department of Chemotherapy of Myeloproliferative disorders, FSFI “National Research Center for Hematology” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation; ORCID Iconhttp://orcid.org/0000-0001-5393-0816View further author information
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Anna N. PetrovaScientific and Advisory Department of Chemotherapy of Myeloproliferative disorders, FSFI “National Research Center for Hematology” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation; View further author information
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Anastasia V. BykovaScientific and Advisory Department of Chemotherapy of Myeloproliferative disorders, FSFI “National Research Center for Hematology” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation; View further author information
,
Adhamjon O. AbdullaevScientific and Advisory Department of Chemotherapy of Myeloproliferative disorders, FSFI “National Research Center for Hematology” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation; ORCID Iconhttp://orcid.org/0000-0003-2530-808XView further author information
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Anna G. TurkinaScientific and Advisory Department of Chemotherapy of Myeloproliferative disorders, FSFI “National Research Center for Hematology” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation; ORCID Iconhttp://orcid.org/0000-0001-9947-2371View further author information
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Sergey I. KutsevLaboratory of Mutagenesis, FSBI “Research Centre for Medical Genetics”, Moscow, Russian Federation; ;Department of Molecular and Cellular Genetics, The Russian National Research Medical University Named after N.I. Pirogov, Moscow, Russian FederationORCID Iconhttp://orcid.org/0000-0002-3133-8018View further author information
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Pages 2512-2515 | Received 17 Aug 2017, Accepted 21 Jan 2018, Published online: 09 Feb 2018
 
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Acknowledgements

We thank A.V. Misurin from Genotechnologia (Moscow, Russian Federation) for BCR/ABL measurements and laboratory of DNA diagnostics (Research Centre for Medical Genetics, Moscow, Russian Federation) for Sanger sequencing.

Potential conflict of interest

Disclosure forms provided by the authors are available with the full text of this article online at https://doi.org/10.1080/10428194.2018.1434880.

Additional information

Funding

This study was supported (in part) by research funding from Ministry of Education and Science of the Russian Federation by agreement 8113 from 28/08/2012 and 8599 from 14/09/2012. The monitoring of the CML patients was supported by the Healthcare Ministry of Russian Federation. SAS received funding of travel, accommodations, or expenses from BioLine and Novartis Farma, AVL received funding of travel from BioLine and Thermo Fisher Scientific Corporation.

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