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Novel translocation of POGZ/STK11 in de novo mast cell leukemia with KIT D816H mutation

Kantaro Ishitsukaa Department of Hematology, University of Tsukuba Hospital, Ibaraki, JapanView further author information

Yuki Yoshizawaa Department of Hematology, University of Tsukuba Hospital, Ibaraki, JapanView further author information

Hidekazu Nishikiia Department of Hematology, University of Tsukuba Hospital, Ibaraki, Japan;b Department of Hematology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan

https://orcid.org/0000-0002-6277-4082 View further author information

Manabu Kusakabea Department of Hematology, University of Tsukuba Hospital, Ibaraki, Japan;b Department of Hematology, Faculty of Medicine, University of Tsukuba, Ibaraki, JapanCorrespondence[email protected]

https://orcid.org/0000-0003-2518-0776 View further author information

Yufu Itoc Department of Hematology, Tsuchiura Kyodo General Hospital, Ibaraki, JapanView further author information

Yukinori Inadomed Department of Pathology, National Hospital Organization Mito Medical Center, Ibaraki, JapanView further author information

Tatsuhiro Sakamotoa Department of Hematology, University of Tsukuba Hospital, Ibaraki, Japan;b Department of Hematology, Faculty of Medicine, University of Tsukuba, Ibaraki, JapanView further author information

Takayasu Katoa Department of Hematology, University of Tsukuba Hospital, Ibaraki, Japan;b Department of Hematology, Faculty of Medicine, University of Tsukuba, Ibaraki, JapanView further author information

Naoki Kuritaa Department of Hematology, University of Tsukuba Hospital, Ibaraki, Japan;b Department of Hematology, Faculty of Medicine, University of Tsukuba, Ibaraki, JapanView further author information

Yasuhisa Yokoyamaa Department of Hematology, University of Tsukuba Hospital, Ibaraki, Japan;b Department of Hematology, Faculty of Medicine, University of Tsukuba, Ibaraki, JapanView further author information

Naoshi Obaraa Department of Hematology, University of Tsukuba Hospital, Ibaraki, Japan;b Department of Hematology, Faculty of Medicine, University of Tsukuba, Ibaraki, JapanView further author information

Yuichi Hasegawaa Department of Hematology, University of Tsukuba Hospital, Ibaraki, Japan;b Department of Hematology, Faculty of Medicine, University of Tsukuba, Ibaraki, JapanView further author information

Yasuhito Nannyae Department of Hematology/Oncology, Institute of Medical Science, University of Tokyo, Tokyo, Japan;f Department of Pathology and Tumor Biology, Kyoto University, Kyoto, JapanView further author information

Seishi Ogawaf Department of Pathology and Tumor Biology, Kyoto University, Kyoto, JapanView further author information

Mamiko Sakata-Yanagimotoa Department of Hematology, University of Tsukuba Hospital, Ibaraki, Japan;b Department of Hematology, Faculty of Medicine, University of Tsukuba, Ibaraki, JapanView further author information

Shigeru Chibaa Department of Hematology, University of Tsukuba Hospital, Ibaraki, Japan;b Department of Hematology, Faculty of Medicine, University of Tsukuba, Ibaraki, JapanView further author information

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Acknowledgment

The authors thank the patient for providing valuable information.

Ethical statements

The study was approved by the institutional review board at University of Tsukuba Hospital. Written informed consent was obtained from the patient and her families.

Disclosure statement

The authors declare no conflict of interest.

Data availability statement

All data and materials are available upon request.

Additional information

Funding

This work was supported by Grants-in-Aid for Scientific Research (KAKENHI: 21J20378[K.I.], 18K16076[M.K.], 21H02945[M.S.-Y.], and 19H03684[S.C.]) from the Ministry of Education, Culture, Sports, and Science of Japan.

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Novel translocation of POGZ/STK11 in de novo mast cell leukemia with KIT D816H mutation

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Novel translocation of POGZ/STK11 in de novo mast cell leukemia with KIT D816H mutation

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