Acknowledgments
The authors wish to thank Associazione Italiana per la Ricerca sul Cancro (AIRC) 5 × 1000, Special Program Metastases (21198), Milan (Italy) to RF; Finanziamento Medi Progetti Universitari 2015 and 2021 to SC (Sapienza University of Rome), and PRIN 2017 (2017PPS2X4_002) to SC.
Author contributions
SC performed experiments, designed research and wrote the manuscript, AT performed experiments and wrote the manuscript, IDS, MC, MA, MDP performed experiment, MM performed statistical analysis, OS, AS, LADN, DC performed experiments, MS performed bioinformatic analysis, VA performed statistical analysis, RB designed the trials, AG and RF designed research and critically revised the manuscript.
Disclosure statement
No potential conflict of interest was reported by the author(s).