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Administration of glucocorticoids prior to liquid biopsy dramatically reduces the detection rate of MYD88 L265P mutation in cerebrospinal fluid of primary CNS lymphoma patients

Haruhiko Takahashia Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, JapanView further author information

Manabu Natsumedaa Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, JapanCorrespondence[email protected]
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Jotaro Ona Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, JapanView further author information

Jun Watanabea Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, JapanView further author information

Mari Tadab Department of Pathology, Brain Research Institute, Niigata University, Niigata, JapanView further author information

Hiroshi Shimizub Department of Pathology, Brain Research Institute, Niigata University, Niigata, JapanView further author information

Yoshihiro Tsukamotoa Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, JapanView further author information

Masayasu Okadaa Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, JapanView further author information

Makoto Oishia Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, JapanView further author information

Jun Takizawac Department of Hematology, Endocrinology and Metabolism, Niigata University Faculty of Medicine, Niigata, JapanView further author information

Yasuhiko Hayashid Department of Neurosurgery, Kanazawa Medical University, Ishikawa, JapanView further author information

Yasufumi Masakie Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, JapanView further author information

Akiyoshi Kakitab Department of Pathology, Brain Research Institute, Niigata University, Niigata, JapanView further author information

Yukihiko Fujiia Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, JapanView further author information

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No potential conflict of interest was reported by the author(s).

Additional information

Funding

This study was funded in part by Japanese Promotion of Science (JSPS) Grants to M.N. [21KK0156], J.W. [19K18418], Y.T. [22K16679], and M.Ok. [20K17955].

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Administration of glucocorticoids prior to liquid biopsy dramatically reduces the detection rate of MYD88 L265P mutation in cerebrospinal fluid of primary CNS lymphoma patients

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Administration of glucocorticoids prior to liquid biopsy dramatically reduces the detection rate of MYD88 L265P mutation in cerebrospinal fluid of primary CNS lymphoma patients

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