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Materials Technology
Advanced Performance Materials
Volume 38, 2023 - Issue 1
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Research Article

Eco-friendly green synthesis of copper nanoparticles from Tinospora cordifolia leaves: optical properties with biological evaluation of anti-microbial, anti-inflammatory and anti-oxidant applications

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Article: 2247908 | Received 29 May 2023, Accepted 10 Aug 2023, Published online: 28 Aug 2023
 

ABSTRACT

The increased use of medicinal plants has raised questions regarding their safety, efficacy, and utility. Since a result, a thorough understanding of plant phytochemical components is essential, since this information will be useful in the development of innovative therapeutic medications. Copper nanoparticles (CuNPs) have received a lot of interest due to their numerous applications. The physical and chemical features of CuNPs influence their uses. In the current study, CuNPs were synthesised utilising the chemical reduction process, with Tinospora cordifolia extract serving as a reducing agent due to their high phenolic and flavonoid content and their antibacterial and anti-inflammatory properties were also assessed. The majority of the absorption peaks found in the T. cordifolia leaves extract can also be found in the FT-IR spectrum of CuNPs, often at the same locations or with just little variations in the peak’s location and intensity. Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM) found that the particles were generally spherical, with an average particle size of 15 to 70 nm. Their potential as anti-bacterial and antifungal drugs was demonstrated by the antimicrobial activity, they exhibited against S. aureus (18 mm), L. bacillus (22 mm), S. mutans (24 mm), and C. albicans (15 mm). Studies on the anti-inflammatory properties of biologically produced Cu NPs were determined.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Data availability statement

The authors confirm that the data supporting the findings of this study are available within the article.

Additional information

Funding

The authors acknowledge and extend their appreciation to the Researchers Supporting Project Number (RSP2023R124), King Saud University, Riyadh, Saudi Arabia.