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Amyloid
The Journal of Protein Folding Disorders
Volume 14, 2007 - Issue 4
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Original Article

An overview of high-dose melphalan and stem cell transplantation in the treatment of AL amyloidosis

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Pages 261-269 | Published online: 06 Jul 2009
 

Abstract

AL amyloidosis is the most common form of systemic amyloidosis and is associated with an underlying plasma cell dyscrasia. This review outlines an overview of high-dose intravenous melphalan and stem cell transplantation in the treatment of AL amyloidosis. An algorithm of our recommendations for the treatment of AL amyloidosis is also outlined.

Abbreviations
HDM/SCT=

high-dose melphalan and stem cell transplantation

CR=

hematologic complete response

FLC=

serum free light chain concentration

TRM=

treatment-related mortality

Abbreviations
HDM/SCT=

high-dose melphalan and stem cell transplantation

CR=

hematologic complete response

FLC=

serum free light chain concentration

TRM=

treatment-related mortality

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