Publication Cover
Amyloid
The Journal of Protein Folding Disorders
Volume 15, 2008 - Issue 1
39
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Letter to the Editor

Secondary amyloidosis associated with histiocytosis X

, , , , , , , & show all
Pages 69-71 | Published online: 06 Jul 2009
 

Abstract

We report a 34-year-old man diagnosed with Langerhans cell histiocytosis (LCH) or histiocytosis X in 1980. He had multiple focal osseous lesions, difficult control of the disease activity and was treated many times with chemo- and radiotherapy for symptomatic control. His kidney disease started 20 years after the diagnosis with progressive renal failure and increasing non-nephrotic proteinuria, coinciding with two flares of LCH. A percutaneous renal biopsy demonstrated amyloidosis. There is only one case described in the amyloidosis literature associated with LCH.

Abbreviations
LCH=

Langerhans cell histiocytosis

Abbreviations
LCH=

Langerhans cell histiocytosis

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