Isolated bilateral fornix anterior columns infarction with acute amnesia and fiber tracts damage, a case report

ABSTRACT

Isolated fornix anterior column infarction has rarely been described and is difficult to assess accurately using conventional magnetic resonance imaging (MRI). We report the case of a 75-year-old female who experienced acute anterograde amnesia. MRI performed within 24 h after amnesia onset showed an isolated infarction of the bilateral anterior columns of the fornix on diffusion-weighted imaging (DWI). Her symptoms persisted for up to 50 days, and diffusion tensor imaging (DTI) showed disruption of the fiber tracts of the fornix. when acute amnesia syndrome onset, fornix anterior column infarction should be considered, and optimized DWI and DTI methods are needed to study the fornix in vivo in future research.

KEYWORDS:

• Isolated fornix infarction
• acute anterograde amnesia
• MRI
• DWI
• DTI

Abbreviations

MRI	=	Magnetic resonance imaging,
DWI	=	Diffusion-weighted imaging,
DTI	=	Diffusion tensor imaging

Disclosure statement

No potential conflict of interest was reported by the author(s).

Authors’ contributions

All the authors have participated in the clinical data collection and analysis. WT-Y validated the data and wrote the first draft of the manuscript; FQ T critically reviewed and revised the manuscript.

Availability of data and material

The datasets generated and/or analyzed during the current study are available from the corresponding author upon reasonable request.

Ethics approval

The study was approved by the Ethics Committee of our hospital.

Consent to participate

Informed consent was obtained from all individual participants for whom identifying information is included in this article.

Additional information

Funding

The author(s) reported there is no funding associated with the work featured in this article.