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Laboratory research

Correlates of Overlapping Fatigue Syndromes

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Pages 247-259 | Published online: 13 Jul 2009
 

Abstract

Purpose: To identify significant behavioural and somatic symptoms associated with formal receipt of a chronic fatigue syndrome diagnosis.

Design: Retrospective cross‐sectional analysis of patient self‐report questionnaires held on a computerized database.

Materials and Methods: Analysis of self‐report responses to a questionnaire from patients referred from a UK clinic specializing in the diagnosis and treatment of fatigue disorders (n=371), 259 of whom were formally diagnosed either exclusively or combinatorially with fatigue diagnoses of myalgic encephalomyelitis, chronic fatigue syndrome and fibromyalgia.

Results: Non‐parametric (chi‐squared) analysis showed that 17 response items (current and historical behavioural/somatic variables) were significantly associated with patients formally diagnosed with fatigue disorders (p<0.01).

Conclusions: The presence of current and historical variables outside of the traditional diagnostic framework of fatigue syndromes provides preliminary evidence for a redefinition of exclusive overlapping fatigue syndromes into a more general spectral model.

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