Investigation of 'borderline' dementia, particularly of Alzheimer's type, compared with non-demented patients with similar neuropsychological profiles

Abstract

INTRODUCTION: The aim of the study was to test the fine ability of the Cambridge Cognitive Examination (CAMCOG) to differentiate between subjects with mild dementia and non-demented subjects. MATERIAL AND METHODS: Ninety-four subjects took part in the study (56 non-demented and 38 mildly demented). Diagnosis was reached according to DSM-IV and NINCDS-ADRDA criteria. RESULTS: Items 160, 146, 171 and 178 seemed to be particularly useful for the diagnosis for subjects under 75 years of age, and items 139, 143, 146, 148, 159, 175, 177, 181, 183 and 186 for the diagnosis for subjects over 74. DISCUSSION: Further study of these items may increase ability to detect dementia in epidemiological surveys and advance knowledge about the role of factors like education or culture in interaction with advanced age. Currently, it is not possible to identify dementia at an early stage by neuropsychological methods alone. ( Int J Psych Clin Pract 2001; 5:55-61)

• Neuropsychology Alzheimer'S Disease Camcog Dementia Diagnosis Mmse