Evaluation of the relationship of the T and M stage with the erector spinae muscle area in male lung cancer patients

Abstract

Objectives

Sarcopenia is very common due to cachexia and presents with a decrease in skeletal muscle mass. In this study, we aimed to investigate the relationship between the T, M category and the erector spinae muscle area (ESMa).

Material and methods

The initial first thorax and high-resolution computed tomography (CT) of patients with lung cancer between 2015 and 2019 were retrospectively screened. After exclusion criterias remaining 226 male patients constituted the study group. ESMa was measured manually in the section taken from the T12 vertebra spinous process level as previously described in the literature and its relationship with the T and M stage were evaluated.

Results

The mean ages of patients were 70 ± 9.57 years. The T stage was T1 in 34 (15%) patients, T2 in 46 (20.4%), T3 in 59 (26.1%), and T4 in 87 (38.5%). Metastasis was detected in 83 (36.7%) patients. The mean ESMa of the patients was 34.15 ± 7.21 mm² and did not differ according to the T stage (p = .39). ESMa was lower in the metastatic group (mean 30.42 ± 6.38 mm²) than the non-metastatic group (mean 36.32 ± 6.78 mm²) (p = .0001).

Conclusions

ESMa, one of the indicators of sarcopenia, is lower in patients with metastatic lung cancer than in nonmetastatic.

Keywords:

• Computed tomography
• erector spinae
• lung cancer
• sarcopenia
• TNM staging

Author contributions

Nevin Aydin and Elif Gundogdu designed and performed the experiments and analyzed the data. Nevin Aydin wrote the manuscript in consultation with Elif Gundogdu.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Data availability statement

The data that support the findings of this study are available from the corresponding author upon reasonable request.

Correction Statement

This article has been corrected with minor changes. These changes do not impact the academic content of the article.

Additional information

Funding

The authors received no financial support for the research, authorship, and/or publication of this article.