Subcutaneous testosterone pellet therapy for reversal of male osteoporosis: a review and case report

Abstract

Purpose

To describe the effects of consistent levels of testosterone in a pellet form and it’s potential to reverse osteoporosis.

Methods

This is a descriptive case report of a 54 year male with a spontaneous fracture and osteoporosis in the presence of what many consider a normal male testosterone level.

Results

After discovering and documenting osteoporosis by DXA scan, the patient was shown to reverse the diagnosis of osteoporosis in a year on pelleted testosterone therapy. Consistent levels of 943 ng/dL were achieved; the patient also experienced improvements in quality of life and sleep apnea.

Conclusion

Testosterone deficiency (TD) is a clinical syndrome and osteoporosis can be found in levels above standard “criteria” of 300. This patient did not realize a benefit on injections both physical and clinically and both improved on pelleted testosterone. This should be further studied and considered for TD in men.

Keywords:

• Testosterone
• testosterone replacement therapy
• osteoporosis
• pellet therapy

Disclosure statement

Dr. Bruce Dorr is an educational consultant for BioTE. Dr. Ahmed Abel Aziz has no disclosures. Dr. Mickey Karram is a research consultant for BIoTE.

Additional information

Funding

The author(s) reported there is no funding associated with the work featured in this article.