A case of pulmonary cryptococcosis followed by pleuritis in an apparently immunocompetent patient during fluconazole treatment

Koichi Izumikawa Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, JapanCorrespondence[email protected]

Yong Zhao Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan

Kohei Motoshima Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan

Takahiro Takazono Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan

Tomomi Saijo Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan

Sintaro Kurihara Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan

Shigeki Nakamura Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan

Taiga Miyazaki Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan

Masafumi Seki Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan

Hiroshi Kakeya Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan

Yoshihiro Yamamoto Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan

Katsunori Yanagihara Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan; Department of Laboratory Medicine, Nagasaki University School of Medicine, Nagasaki, Japan

Yoshitsugu Miyazaki Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan

Tomayoshi Hayashi Department of Pathology, Nagasaki University School of Medicine, Nagasaki, Japan

& Shigeru Kohno Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan

show all

Abstract

Cryptococcal pleuritis is rare in individuals with no underlying disease. We report a case of pulmonary cryptococcosis followed by pleuritis in a patient on fluconazole treatment. Biopsy of the pleura revealed a granuloma and a cryptococcal body, while PCR and sequence analysis of extracted DNA from the pleura proved the presence of Cryptococcus species, most likely C. neoformans. Voriconazole with flucytosine and drainage of the pleural effusion were effective in treating the patient.

Keywords

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

A case of pulmonary cryptococcosis followed by pleuritis in an apparently immunocompetent patient during fluconazole treatment

Information for

Open access

Opportunities

Help and information

A case of pulmonary cryptococcosis followed by pleuritis in an apparently immunocompetent patient during fluconazole treatment

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature