Managing vasomotor symptoms effectively without hormones

Abstract

Vasomotor symptoms (hot flushes and/or night sweats) affect approximately 80% of women over the menopause transition and can affect quality of life, productivity, and relationships. Vasomotor symptoms are the main reason for seeking treatment during the menopausal transition. Although menopausal hormone therapy (MHT) is effective for symptom management, the majority of symptomatic women do not take MHT. In this article, we review the evidence for non-hormonal treatments for vasomotor symptoms, including pharmacological and non-pharmacological approaches, and provide a clinical algorithm for managing symptomatic women.

摘要

血管舒缩症状（潮热和/或盗汗）在绝经过渡期影响约80％的女性, 并可能影响生活质量、生产力和人际关系。血管舒缩症状是绝经过渡期寻求治疗的主要原因。尽管绝经激素疗法（MHT）对于症状管理有效, 但是大多数有症状的女性不服用MHT。在本文中, 我们回顾了非激素治疗血管舒缩症状的证据, 包括药理学和非药理学方法, 并提供了管理有症状女性的临床算法。

Keywords:

• Menopause
• vasomotor
• hot flush
• non-hormonal
• menopausal hormone therapy
• non-pharmacological
• breast cancer

Potential conflict of interest

M Hickey has received funding from QUE oncology for a clinical trial of non-hormonal treatments for vasomotor symptoms.

Source of funding

Nil.