Abstract
In targeting molecules, destinated for treatment of skin ageing, we synthesized esters of hesperitin (4′-methoxy-5,7,3′-trihydroxyflavanone). Esterification with lauric acid was used with the aim to overcome the flavonoid instability and to improve the therapeutic usefulness. Stability, free radical scavenging activity and anti-elastase potency of the prepared compounds were studied and compared to those of hesperitin (natural compound). Compounds obtained are more stable than hesperitin and display similar or higher anti-elastolytic and free radical scavenging activities.