Study of the Molluscicidal Activity of Some Phenolic Compounds: Structure-Activity Relationship

Abstract

The relationship between the structure of 14 phenolic compounds and their molluscicidal activity against the molluscan intermediate host of urinary schistosomiasis, Bulinus truncatus, is discussed. It was found that among flavonoids tested, unhydroxylated flavone compound and flavanone hesperidin were the most active (LC₅₀ = 5.47 and 8.91 ppm, respectively), whereas gallic acid compound with para-methoxy group was the most effective among phenolic acids tested (LC₅₀ = 3.60 ppm). These results are encouraging and prove other biological application of these compounds.

Keywords: :

• Bulinus Truncatus
• Flavonoids
• Molluscicidal Activity
• Phenolic Acids
• Schistosomiasis Control