Aldose Reductase Inhibitors from Stellera chamaejasme.

Baomin Feng College of Bioengineering, Dalian University, Dalian, China

Tao Wang Department of Pharmacognosy, Kyoto Pharmaceutical University, Kyoto, Japan

Yi Zhang Department of Analytical Chemistry, Kyoto Pharmaceutical University, Kyoto, Japan

Huiming Hua School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, China

Jingming Jia School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, China

Hailong Zhang School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, China

Yuehu Pei School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, China

Liying Shi College of Bioengineering, Dalian University, Dalian, China

Yongqi Wang College of Bioengineering, Dalian University, Dalian, China

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Abstract

Six biflavonoids (chamaejasmin, 7-methoxyneochamaejasmin, 7-methoxychamaejasmin, chamaejasmenin B, chamaechromone, wikstrol A) from Stellera chamaejasme. L. have been assayed to show good aldose reductase inhibiting activity. These compounds may be useful to improve diabetic complications such as neuropathy, cataract formation, neophropathy, and retinopathy.

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Aldose Reductase Inhibitors from Stellera chamaejasme.

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