Cell Cycle Inhibitory Activity of 137 Traditional Chinese Herbal Medicines Against tsFT210 Cell Line

ABSTRACT

One hundred thirty-seven species of traditional Chinese herbal medicines belonging to 61 families were collected from Yunnan and Sichuan province in the People's Republic of China and tested for cell cycle inhibitory activity against tsFT210 cell line. Thirty-one traditional Chinese medicines from 18 families showed bioactivity, and the ethanol extract of Rubus aleaefolius. Poir. rhizome and Trewia nudiflora. L. rhizome exhibited the strongest inhibitory activity on cell cycle progression at the G₀/G₁ and G₂/M phases, respectively. The screening results indicated that this bioassay is suitable for screening bioactive natural products from herbal medicines.

Keywords:

• Cell cycle
• traditional Chinese herbal medicines
• tsFT210