Abstract
The in vitro. antifungal activity of aqueous, ethanol, chloroform, petroleum ether, and residue extracts from 10 indigenous Bahraini plants used in folk medicine for the treatment of various diseases is reported. Extract efficacy was evaluated using the agar well diffusion assay against four filamentous fungi and two yeasts monitored by standard antifungal disks. The results showed that all but, in particular, ethanol and chloroform plant extracts reveal variable degrees of bioactivity against at least two of the tested microbes. The highest ethanol extract activity was exhibited by Cressa cretica. (L.) against Penicillium citrinum. Thom (32.2 mm) followed by Candida albicans. (C. P. Robin) Berkhout (25.7 mm). The diffusable metabolites of Heliotropium curassavicum. L. also demonstrated marked inhibitory effects against the same microorganisms. Chloroform extracts of Emex spinosa. Campd. displayed an elevated potency against Alternaria alternata. (Fries) Keissler (27.9 mm) and Saccharomyces cerevisiae. Meyen ex. E. C. Hansen (27.5 mm). Zone of inhibition against other fungi varied from 19.9 to 25.9 mm. However, the highest growth inhibition was encountered with Fagonia indica. Burm F. against P. citrinum. (29.3 mm). With the exception of chloroform extracts from cultivated soils, various extracts of plants randomly collected from saline-affected soils exhibited higher fungal radius inhibition than plants from cultivated soils. The significance of these results in relation to ethnobotanical data is discussed.