Antibacterial and Phytochemical Studies on the Stem of Suregada angustifolia. from Peninsular India

Abstract

Phytochemical analysis of the stem bark of Suregada angustifolia. (Baill. ex Muell. Arg.) Airy Shaw resulted in the isolation of six known compounds: friedelin, epi-friedelinol, n.-octacosanol, α.-amyrin, β.-sitosterol, and β.-sitosterol-3 β.-D-glucopyranoside. The aqueous and various solvent (methanol, chloroform, and hexane) extracts of stem bark were tested by the agar well-diffusion method against 12 human pathogenic bacteria. Maximum antibacterial activity was observed in the order of chloroform, hexane, and methanol extracts. Aqueous (room temperature, boiled, and autoclaved) extracts did not demonstrate any activity. The results of the current investigation correspond positively with the claims of the ethnomedicinal uses.

Keywords:

• Antibacterial activity
• ethnomedicine
• Euphorbiaceae
• human pathogenic bacteria
• Peninsular India
• phytochemistry
• skin infections
• stem
• Suregada angustifolia