4,184
Views
10
CrossRef citations to date
0
Altmetric
Research Article

Antidiabetic Activity of Some Indian Medicinal Plants

, , , , &
Pages 95-99 | Accepted 01 Dec 2005, Published online: 07 Oct 2008
 

Abstract

The effect of aqueous extracts of Syzygium cumini. Linn., Gymnema sylvestre. (Retz.) Schult., and Portulaca olearacea. Linn. were investigated in fasting normal and streptozotocin (STZ)-induced diabetic rats. The effects of extracts on oral glucose tolerance in normal fasting rats were also studied. The aqueous extracts of S. cumini. (200 mg/kg) and G. sylvestre. (200 mg/kg) decreased the blood glucose in normal rats significantly at 2 and 4 h of extract administration (p < 0.05, p < 0.01). The S. cumini. and G. sylvestre. extracts decreased the increase of glucose levels significantly (p < 0.05) at 90 and 180 min after the glucose load in glucose tolerance test. In STZ diabetic animals, the aqueous extracts of S. cumini. and G. sylvestre. decreased the blood glucose significantly (p < 0.05) at 4 h. The aqueous extract of P. olearacea. did not show any hypoglycemic activity.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.