Antifungal Activity of the Essential Oil of Mentha. x piperita.

Marina D. Soković Institute for Biological Research, S. Stanković, Belgrade, Serbia and Montenegro

Jasmina Glamočlija Institute for Biological Research, S. Stanković, Belgrade, Serbia and Montenegro

Petar D. Marin Institute of Botany, Faculty of Biology, Belgrade University, Belgrade, Serbia and Montenegro

Dejan D. Brkić Institute for Medicinal Plant Research “Josif Pančić,” Belgrade, Serbia and Montenegro

Jelena Vukojević Institute of Botany, Faculty of Biology, Belgrade University, Belgrade, Serbia and Montenegro

Dragutin Jovanović Center for Preventive Medicine, VMA, Belgrade, Serbia and Montenegro

Nina Bulajić Center for Preventive Medicine, VMA, Belgrade, Serbia and Montenegro

Dragan Kataranovski Institute for Biological Research, S. Stanković, Belgrade, Serbia and Montenegro

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Abstract

The in vivo. evaluation of toxicological and antifungal activity of the Mentha. x piperita. L. essential oils and menthol was made on 2-month-old male Wistar rats. We examined the therapeutic potency against experimentally induced dermatomycoses in rats using the most frequent dermatomycetes, Trichophyton mentagrophytes., T. rubrum., and T. tonsurans.. The therapeutic efficacy of 1% solution of essential oil and menthol, as well as commercial preparation bifonazole, was evaluated. During the 36-day observation period, the oil-treated animals were cured completely.

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Antifungal Activity of the Essential Oil of Mentha. x piperita.

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Antifungal Activity of the Essential Oil of Mentha. x piperita.

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