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Research Article

Cytotoxic Effects of Taxodium distichum. Oils

, , , , &
Pages 106-110 | Accepted 29 Aug 2006, Published online: 07 Oct 2008
 

Abstract

The leaves and fruits of Taxodium distichum. (L.) L. C. Rich. (Taxodiaceae) collected from Nigeria were subjected to hydrodistillation. The essential oils obtained were analyzed by gas chromatography–mass spectrometry (GC-MS). The main compounds were α-pinene (60.5%) and thujopsene (17.6%) from the fruits and thujopsene (27.7%), pimara-8(14),15-diene (13.1%), widdrol (12.8%), and β.-caryophyllene (11.4%) from the leaves. The oils exhibited pronounced cytotoxic activities against PC-3, Hep G2, and Hs 578T human tumor cell lines at tested concentrations. Only the fruit oil displayed a promising antifungal effect (MIC 19.5 µg/mL) against Aspergillus niger..

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