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Abstract
Aloe vera. L. (Aloeaceae) has been extensively studied for anti-inflammatory, antimicrobial, and cellular regeneration properties. This work evaluated in vivo. the effects of powder of freeze-dried Aloe vera. on rat pulp tissue. Pulp tissue was mechanically exposed to Aloe vera., and it was evaluated at 1 to 30 days after the procedure by histopathologic examination. A predominant acute-moderate inflammatory infiltrate was observed in the Aloe vera.–treated group 1 to 7 days after treatment. At 14 to 30 days, pulp tissue took a normal pattern when comparing Aloe vera. treatment with the Ca(OH)2 treatment; it was found that both treatment groups stimulated reparative dentin and the formation of complete bridge. Strong superficial necrosis was detected exclusively for Ca(OH)2. It seems evident that application of Aloe vera. in direct contact with the exposed pulp has acceptable biocompatibility and can lead to tertiary bridge formation.