Antibacterial and Antifungal Activities of the Constituents of Flemingia paniculata.

Abstract

A salicylic acid derivative (1), a cinnamaldehyde (2), and six isoflavones (3–8) from the stem bark of Flemingia paniculata. Wall. (Leguminosae) were tested for antibacterial (both Gram-positive and Gram-negative) and antifungal activities. All the compounds showed significant activities against the test organisms having MIC values in the range of 1.57–200 μ g/mL. The highest potency (MIC = 1.57 μ g/mL) was exhibited by 3 against Staphylococcus aureus..

Keywords:

• Antibacterial
• antifungal
• Flemingia paniculata
• Leguminosae