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Abstract
The tail flick, the acetic acid writhing, the croton oil-induced mouse ear edema, and carrageenan-induced peritonitis tests were used to study the anti-inflammatory effects of the alcohol extract from Pterodon emarginatus Vogel. (Leguminosae/Fabaceae) stem bark. The alcohol extract caused inhibition of acetic acid-induced abdominal writhing, reducing the number of leukocytes (x 107) per mL of peritoneal wash and ear edema formation. The results suggest that Pterodon emarginatus stem bark contains compounds with analgesic and anti-inflammatory actions.
Acknowledgements
The authors are grateful to Ekaterina A. F. B. Rivera and Jackson Nascimento de Lima for technical assistance. Thanks are also due to CAPES, CNPq, FUNAPE/UFG for financial support.
Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.