Imaging and pathological features of gastric lesion of immunoglobulin G4-related disease: A case report and review of the recent literature

Dai InoueDepartment of Radiology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan,

Norihide YonedaDepartment of Radiology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan,

Kotaro YoshidaDepartment of Radiology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan,

Hiromi NukaDivision of Rheumatology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan,

Jun KinoshitaDepartment of Gastroenterological Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan,

Sachio FushidaDepartment of Gastroenterological Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan,

Fumihito ToshimaDepartment of Radiology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan,

Tetsuya MinamiDepartment of Radiology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan,

Masayuki TakahiraDepartment of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan, and

Shoko HamaokaDepartment of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan, and

Hiroko IkedaDivision of Pathology, Kanazawa University Hospital, Kanazawa, Japan

Toshifumi GabataDepartment of Radiology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan,

Mitsuhiro KawanoDivision of Rheumatology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan, Correspondence[email protected]

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Abstract

We describe a 67-year-old man with immunoglobulin G4-related disease (IgG4-RD) presenting with optic neuropathy, dacryoadenitis, periaortitis, retroperitoneal fibrosis, and a gastric mass-like lesion. A mass-like lesion measuring 52 × 40 mm in the antrum of the stomach was found incidentally through whole-body screening for other organ involvement of IgG4-RD using contrast-enhanced computed tomography (CT). Histology of the stomach revealed that the lesion was also IgG4-related and was located in the submucosal layer extending to the subserosal region. This case suggests that the stomach can also be a site of involvement of IgG4-RD.

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Imaging and pathological features of gastric lesion of immunoglobulin G4-related disease: A case report and review of the recent literature

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Imaging and pathological features of gastric lesion of immunoglobulin G4-related disease: A case report and review of the recent literature

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