An efficient synthesis of bis(indolyl)methanes and evaluation of their antimicrobial activities

Abstract

A versatile and efficient method has been developed for the synthesis of bis(indolyl)methanes by using aluminium triflate (0.5 mol%) as a novel catalyst. Further, some of the synthesized compounds were evaluated for their efficacy as antibacterial and antifungal activities. Most of the compounds have shown moderate to good inhibitory activity.

• Bis(indolyl)methanes
• aluminium triflate
• antibacterial activity
• antifungal activity

Acknowledgements

The authors (M.N.A.K., K.S.R. and S.K.A.) thank CSIR and the author (Y.V.V.S) thanks UGC, New Delhi, for the award of research fellowship.

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.