Fetomaternal alloimmune thrombocytopenia: The questions that still remain

Abstract

Fetomaternal alloimmune thrombocytopenia (FMAIT) occurs when maternal antibodies are formed to fetal platelet antigens, leading to thrombocytopenia and hemorrhagic complications. The diagnosis is frequently made only after a major hemorrhagic event has occurred during a pregnancy. Identifying patients at risk remains difficult, and the optimal treatment regimen remains to be determined.

Keywords:

• Neonatal alloimmune thrombocytopenia
• fetal-maternal thrombocytopenia
• platelet alloantigens
• intracranial hemorrhage