Different medicaments in fetus maturation–corticosteroid usage

Abstract

Objective. The object of work is pointing out the significance of improvement highly risk pregnancies by applying artificial fetal lungs maturation in relation to expected outcomes without adequate therapy.

Methods. We analyzed fetal lung maturation by using lecithin and sphingomyelin ratio in embryo fluid received by foam test. We examined successfulness of artificial fetal lungs maturation by applying corticosteroids to the embryo in a group of patients with serious form of growth retardation (group A), then to the mother (group B) and by inducing partial mild form of asphyxia with oxytocin infusion (group C).

Results. The success of the method is shown by the success of finished pregnancies. We followed the difference between expected and actual term of delivery.

Conclusion. Artificial fetal lungs maturation by applying fetal corticosteroids efficiently increases the creation of lecithin and sphingomyelin and enables life of neonate even in period up to 30^th week of gestation.

Keywords:

• Artificial fetal lungs maturation
• corticosteroids
• neonate

Notes

*It is evident that group A (which received emergency therapy for lungs maturation) was at greater risk, and that a larger number of pathological mechanisms was based on hypertension changes in pregnancy; this is also a pattern in literary data about clinical necessity of administering acute, efficient therapy in hypertensive states of mother and excessive disturbance of fetal flow.