Placenta accreta spectrum disorders in twin pregnancies as an under reported clinical entity: a case series and systematic review

Giuseppe Calia Department of Obstetrics and Gynecology, Ospedali Riuniti, Palermo, Italy

Francesco Labatea Department of Obstetrics and Gynecology, Ospedali Riuniti, Palermo, Italy

Gaspare Cucinellaa Department of Obstetrics and Gynecology, Ospedali Riuniti, Palermo, Italy

Manuela Fabioa Department of Obstetrics and Gynecology, Ospedali Riuniti, Palermo, Italy

Danilo Bucab Centre for Fetal Care and High-Risk Pregnancy, Department of Obstetrics and Gynecology, University of Chieti, Chieti, Italy

Raffaella Di Girolamob Centre for Fetal Care and High-Risk Pregnancy, Department of Obstetrics and Gynecology, University of Chieti, Chieti, Italy

Asma Khalilc Fetal Medicine Unit, Saint George’s University of London, London, United Kingdom;d Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George’s University of London, London, United Kingdom;e The Twins Trust Centre for Research and Clinical Excellence, Saint George’s Hospital, London, United Kingdom

Francesco D’Antoniob Centre for Fetal Care and High-Risk Pregnancy, Department of Obstetrics and Gynecology, University of Chieti, Chieti, ItalyCorrespondence[email protected]

https://orcid.org/0000-0002-5178-3354

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Abstract

Recent reports suggested a potential association between twin pregnancy and the occurrence of placenta accreta spectrum (PAS) disorders. Despite this, scarce data on PAS disorders in twins has been reported in the published literature. We present a series of twelve twin pregnancies complicated by PAS from two large institutions over 5 years. A systematic review of the literature was also conducted in order to find studies reporting on the risk factors, prenatal diagnosis using ultrasound and clinical outcomes of PAS in twin pregnancies.

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Placenta accreta spectrum disorders in twin pregnancies as an under reported clinical entity: a case series and systematic review

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Placenta accreta spectrum disorders in twin pregnancies as an under reported clinical entity: a case series and systematic review

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