Acknowledgments
The authors thank Dr. Claudio Gobbi (Neurocenter of Southern Switzerland) for helpful comments and suggestions.
Declaration of interest
H Dalton has had travel and accommodation costs and consultancy fees from GlaxoSmithKline, Wantai, and Roche; travel, accommodation and lecture fees from Merck, Gilead and GFE Blut GmBh; travel and accommodation fees from the Gates Foundation and Médecins Sans Frontières and a grant from BMA. V E Jeroen has had consultancy and/or lecture fees from Merck, Genzyme, Biogen, Novartis and Teva. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. Peer reviewers on this manuscript have no relevant financial or other relationships to disclose.