Thiol/Disulfide Homeostasis in Patients with Molar Pregnancies

Meryem Kuru PekcanDepartment of Obstetrics and Gynecology, Dr. Zekai Tahir Burak Women's Health Education and Research Hospital, University of Health Sciences, Ankara, Turkey; Correspondence[email protected]

Aytekin TokmakDepartment of Obstetrics and Gynecology, Dr. Zekai Tahir Burak Women's Health Education and Research Hospital, University of Health Sciences, Ankara, Turkey;

Nazli Topfedaisi OzkanDepartment of Obstetrics and Gynecology, Dr. Zekai Tahir Burak Women's Health Education and Research Hospital, University of Health Sciences, Ankara, Turkey;

Gulnur OzaksitDepartment of Obstetrics and Gynecology, Dr. Zekai Tahir Burak Women's Health Education and Research Hospital, University of Health Sciences, Ankara, Turkey;

Arzu KosemDepartment of Clinical Biochemistry, Ankara Numune Training and Research Hospital, University of Health Sciences, Ankara, Turkey;

Ozcan ErelDepartment of Clinical Biochemistry, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey;

Mutlu MeydanliDepartment of Obstetrics and Gynecology, Dr. Zekai Tahir Burak Women's Health Education and Research Hospital, University of Health Sciences, Ankara, Turkey;

show all

Abstract

Introduction: We aimed to investigate serum dynamic thiol and disulfide levels in patients with molar pregnancy (MP), and compare these concentrations with those of healthy pregnant women. Materials and Methods: Forty-one patients who were diagnosed with MP and 41 gestational age-matched healthy pregnant women were included in this prospective study. MP cases were separated in two groups as complete hydatidiform mole (CHM) and partial hydatidiform mole (PHM). Demographic features and thiol/disulfide homeostasis were recorded for each woman. Results: There was a significant correlation between the decrease in the total thiol and native thiol levels in MP patients. However, no significant difference was observed between CHM and PHM groups in terms of serum disulfide levels. Conclusion: OS is increased in MPs both in complete and partial moles, as determined by thiol/disulfide analysis.

Keywords:

Disclosure statement

All authors have no conflict of interest.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Thiol/Disulfide Homeostasis in Patients with Molar Pregnancies

Information for

Open access

Opportunities

Help and information

Thiol/Disulfide Homeostasis in Patients with Molar Pregnancies

Abstract

Disclosure statement

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature