Herpes Simplex Virus: Fetal and Decidual Infection

Robert W. Bendon Department of Pathology and Laboratory Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, 45267

, MD,

Fernando Perez Department of Pathology and Laboratory Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, 45267

, MD &

Mukunda B. Ray Department of Pathology and Laboratory Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, 45267

, MD

Abstract

We report 2 cases of probable in-utero transmission of herpes simplex virus. Herpes viral antigen was localized in these cases to the decidualized endometrium, using an immunoperoxidase staining technique. Routine histology did not show herpes inclusions in the decidual or glandular cells. This finding suggests that herpes virus may infect endometrial cells during pregnancy.

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Herpes Simplex Virus: Fetal and Decidual Infection

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Herpes Simplex Virus: Fetal and Decidual Infection

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