Reversal of Brugada electrocardiographic pattern with sodium bicarbonate solution after amitriptyline overdose

Abstract

A Brugada electrocardiographic pattern (BEP) associated with tricyclic antidepressant (TCA) overdose has been reported rarely, but its reversal by sodium bicarbonate has not been described previously. We reported a case of amitriptyline overdose induced Type 1 BEP which was reversed by 150 mEq of intravenous sodium bicarbonate.

Keywords:

• Brugada electrocardiographic pattern
• Antidepressants
• ECG changes
• Sodium bicarbonate