Genetic susceptibility to nicotine and/or alcohol addiction: a systematic review

Isabel Legaza University of Murcia - Espinardo Campus, Murcia, SpainCorrespondence[email protected]

M. D. Pérez-Cárcelesb Department of Legal and Forensic Medicine, Biomedical Research Institute (IMIB), Regional Campus of International Excellence “Campus Mare Nostrum”, Faculty of Medicine, University of Murcia, Murcia, Spain

https://orcid.org/0000-0003-1879-2969

Irene de la Callea University of Murcia - Espinardo Campus, Murcia, Spain

Fuensanta Arjonaa University of Murcia - Espinardo Campus, Murcia, Spain

Miriam Rocaa University of Murcia - Espinardo Campus, Murcia, Spain

Pablo Cejudoa University of Murcia - Espinardo Campus, Murcia, Spain

Aurelio Lunaa University of Murcia - Espinardo Campus, Murcia, Spain

https://orcid.org/0000-0001-7760-7415

Eduardo Osunaa University of Murcia - Espinardo Campus, Murcia, Spain

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Abstract

Recent studies have confirmed the wide consumption of tobacco and alcohol in our society and the strong addiction generated by these substances, which is responsible for high public health expenditure. Understanding the biological mechanisms of nicotine and/or alcohol dependence should have huge public health repercussions in the future. The aim of this review was to analyze the main human genes and polymorphisms related to nicotine and/or alcohol addiction, to help understand the biological mechanisms involved and which may be useful for developing new treatments in the future.

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Genetic susceptibility to nicotine and/or alcohol addiction: a systematic review

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Genetic susceptibility to nicotine and/or alcohol addiction: a systematic review

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