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Research Articles

Volatile toxin of Limonia acidissima (L.) produced larvicidal, developmental, repellent, and adulticidal toxicity effects on Aedes aegypti (L.)

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Pages 119-128 | Received 15 Aug 2020, Accepted 12 Nov 2020, Published online: 23 Dec 2020
 

Abstract

The acute toxicity from volatile toxin from the Limonia acidissima (La-VO) was evaluated on the mosquito, Aedes aegypti. Screening of La-VO showed five major bioactive compounds with a major peak estragole. The mortality rate was significantly greater at 150 ppm La-VO. The lethal concentration (LC50) was observed at 65.24 ppm. Sub-lethal dosage of La-VO resulted in significant changes in developmental times. Enzymatic profile of larvae post treatment showed upregulation of CYP450 and GST levels. A maximum repellent activity was observed at 75 ppm La-VO at 98% up to 210 minutes. The La-VO provided evidence of insecticidal and toxicity to the mosquito.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This research was funded by Researchers Supporting Project number [RSP-2020/123], King Saud University, Riyadh, Saudi Arabia.

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