The effects of opium uses on syntax score of angiography patients with coronary artery disease (CAD)

Abstract

Opium has been used traditionally for lowering blood lipids, diabetes, cancer, and postpone of cardiac diseases. The coronary angiography patients were divided to opium user and control group. SYNTAX score, serum lipid profile, left ventricular ejection fraction (LVEF), systolic and diastolic blood pressure (SBP and DBP) were measured in the case and control groups. The SBP, LVEF, serum levels of triglycerides, creatinine and SYNTAX score in opium user group was significantly lower than non-user group (p < 0.05 to p < 0.01). Although, opium consumption reduced some risk factors, LVEF a key variable for the diagnosis and management of heart failure was also reduced.

Keywords:

• Papaver somniferum
• opium
• coronary artery disease
• SYNTAX score
• lipid profile

Acknowledgements

We thank the research council of Birjand University of Medical Sciences.

Author contributions

S.A.M, and N.A. designed the study and interpreting the data, help to write the manuscript prior to submission. T.K, N.P, N.H.B, F.H and M.S.N. helped to the study design and were involved in the collection and interpretation of data. S.K.B and M.S were involved in the collection, analysis and interpretation of data. M.R.K and were responsible for study design, drafting and revising the manuscript. All authors read and approved the final version of the manuscript.

Disclosure statement

No potential conflict of interest was reported by the authors.