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Abbreviations
| CF | = | Cystic Fibrosis |
| CFTR | = | Cystic Fibrosis Transmembrane Conductance Regulator |
| CFTRm | = | Cystic Fibrosis Transmembrane Conductance Regulator protein modulator |
| HEMT | = | Highly Effective CFTR Modulator Therapy |
| ECFSPR | = | European Cystic Fibrosis Patient Registry |
| pwCF | = | people with Cystic Fibrosis |
| FDA | = | Food and Drug Administration |
| EMA | = | European Medicines Agency |
| MHRA | = | Medicines and Healthcare products Regulatory Agency |
| EEUU | = | United States |
| UK | = | United Kingdom |
| EU | = | European Union |
| EC | = | European Commission |
Declaration of interest
A Felipe Montiel, A Álvarez Fernández and E Polverino have received honoraria from Vertex as speakers. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
Reviewer disclosures
Peer reviewers on this manuscript have no relevant financial or other relationships to disclose.