Implications of blood-brain barrier disruption in ALS

Svitlana Garbuzova-Davis Center of Excellence for Aging & Brain Repair,; Departments of Neurosurgery; Molecular Pharmacology and Physiology,; Pathology and Cell BiologyCorrespondence[email protected]

Samuel Saporta Center of Excellence for Aging & Brain Repair,; Departments of Neurosurgery; Pathology and Cell Biology

Paul R. Sanberg Center of Excellence for Aging & Brain Repair,; Departments of Neurosurgery; Molecular Pharmacology and Physiology,; Pathology and Cell Biology; Psychiatry, University of South Florida, College of Medicine, , Tampa, Florida, USA

Abstract

Our letter to the editor addresses important questions regarding the role of the blood-spinal cord barrier in amyotrophic lateral sclerosis. The novel finding of barrier dysfunction in ALS has implications for disease pathogenesis. This discussion should prove of widespread interest to researchers and may help in formulating various new therapeutic strategies to protect barrier function and thus extend functionality and lifespan in ALS patients.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Implications of blood-brain barrier disruption in ALS

Information for

Open access

Opportunities

Help and information

Implications of blood-brain barrier disruption in ALS

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature